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Can saffron help with sexual disorders in men and women? With and without depression, thus several studies

For many years I am using several Amanprana products. My all-time favorites are Kotobuki Matcha, Gula Java Cacao, Gula Java Safran, Coconut Oil, Botanico Mix and Razoli.

Marco Zielinski, Geschäftsführer, Rhino's energy GmbH, Germany

Preliminary results of the research with saffron: more arousal, more vaginal lubrication and less pain

The “female sexual function index” was used. This index investigates 6 parameters: desire, arousal, vaginal lubrication, orgasm, satisfaction and pain. Side effects were systematically recorded in the course of the process with the aid of a checklist. The major findings of the study: at the end of the fourth week the women in the saffron group scored significantly higher on the total female sexual function index. Primarily the parameters of arousal, vaginal lubrication and pain improved in comparison with the placebo-control group. No significant improvements were observed for the parameters of desire, satisfaction and orgasm. The authors of the study concluded that saffron has aphrodisiac properties.

Saffron and sexual dysfunction. Six studies demonstrate:

In the last three decades six other studies have investigated the effects of saffron on sexual dysfunction (three randomised controlled studies, two case series studies, one crossover study). Heidary et al. carried out a case series study in which 52 non-smoking infertile men were treated with 50 mg saffron that was administered three times a week over a period of three months. A sperm analysis was carried out before and after the treatment (3). The researchers found that saffron had positive effects on the form and mobility of the sperm. Saffron was not able to increase the number of spermatozoids.
In another study with a higher dose of saffron (300mg/day over ten days), Shamsa et al. found significant improvements from self-reported erectile dysfunctions and nocturnal penile tumescence amongst twenty male patients with erectile dysfunctions (4). Saffron can thus reduce sexual dysfunction amongst men and women with severe depression and related sexual dysfunction (with Fluoxetine').

Other studies were not able to prove that saffron increased arousal amongst men (5)(6). Safarinejad et al. compare saffron (60 mg/day) to sildenafil (50 mg/day) amongst 307 men with erectile dysfunction (5). They didn’t find that the saffron had any favourable effect with a dose of 30 mg/day over 12 weeks amongst men with an erectile dysfunction. Studies on a larger scale  could also not demonstrate any differences in sperm parameters amongst 260 infertile men with idiopathic oligoasthenoteratozzspermia (OAT) who had taken 60 mg/day of saffron over 26 weeks in comparison with the placebo group.(6).

Finally, two studies have carried out research into the effects of saffron supplements for the treatment of sexual problems amongst patients with severe depression and a Fluoxetine-induced sexual dysfunction. Modabbernia et al. found that the addition of saffron (30 mg/day over 4 weeks) was effective in the treatment of fluoxetine-related erectile dysfunctions amongst married men with severe depression whose depression was stabilised with Fluoxetine (7).
Kashani et al. support the results of Modabbernia et al. as to the effectiveness and safety of saffron for the treatment of sexual disorders and extend the research results to women with a Fluoxetine-induced sexual disorder (8).

These two studies demonstrate that a dose of 30 mg/day of saffron can lead to improvements in the sexual function of men and women with severe depression and Fluoxetine-induced sexual dysfunction. Saffron didn’t have any side effects in either of the studies. This is a major advantage with regard to the selective serotonin reuptake inhibitors (SSRI), medication which is prescribed for sexual disorders and has significant side effects. Alongside its effect as an antidepressant saffron can have an additional benefit, because it is an aphrodisiac. So saffron can be a useful supplement to SSRIs in the treatment of depression.

Saffron for the treatment of sexual problems amongst patients with depression
Saffron for the treatment of sexual problems amongst patients with depression


Different studies have demonstrated that the use of saffron to treat sexual disorders in men and women with moderate or severe depression gave positive results with the additional advantage that saffron is an aphrodisiac.


1. Agha-Hosseini M, Kashani L, Aleyaseen A, et al. Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial. BJOG. 2008;115(4):515-519.
2. Kashani L, Raisi F, Saroukhani S, et al. Saffron for treatment of fluoxetine-induced sexual dysfunction in women: Randomized double-blind placebo-controlled study. Hum Psychopharmacol Clin Exp. 2012;28(1):54-60.
3. Heidary M, Nejadi JR, Delfan B, et al. Effect of saffron on semen parameters of infertile men. Urol J. 2008;5(4):255-259.
4. Shamsa A, Hosseinzadeh H, Molaei M,Shakeri MT, Rajabi O. Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: A pilot study. Phytomedicine. 2009;16(8):690-693.
5. Safarinejad MR, Shafiei N, Safarinejad S. An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment. Int J Impot Res. 2010;22(4):249-250.
6. Safarinejad MR, Shafiei N, Safarinejad S. A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasthenoteratozoospermia. Phytother Res. 2011;25(4):508-516.
7. Modabbernia A, Sohrabi H, Nasehi AA, et al. Effect of saffron on fluoxetine-induced sexual impairment in me: Randomized double-blind placebo-controlled trial. Psychopharmacology. 2012; 223(4):381-388.
8. Kashani L, Raisi F, Saroukhani S, et al. Saffron for treatment of fluoxetine-induced sexual dysfunction in women: Randomized double-blind placebo-controlled study. Hum Psychopharmacol Clin Exp. 2012;28(1):54-60.

Boost your sex life? Saffon more powerful than ginseng, muira puama, yohimbe, wine, chocolate, Viagra and Cialis.

Do you want to literally ‘spice up’ your sex life? Then try adding ginseng or saffron to your food. A study carried out by the University of Guelph (Canada), led by Massimo Marcone, reveals that these two natural aphrodisiacs are the most efficient, even more so than wine and chocolate, which only appear to have a psychological effect.
Aphrodisiacs have been used for thousands of years, but very few scientific studies have attempted to explain the effects. According to John Melnyk, co-author of the study which was published in the journal Food Research International, this study is the most scientific analysis to date. The authors emphasise that the treatment of erectile disorders with synthetic drugs such as Sildenafil (Viagra) or Tadalafil (Cialis), has numerous side effects, such as headaches, aching muscles, blurred vision and dangerous side effects in combination with other medication or supplements. “In addition, these synthetic drugs don’t result in increased libido”, emphasises Melnyk.

The scientists, who have analysed all the existing studies of stimulating substances, have established that only three substances improve sexual function: ginseng, saffron and yohimbine, an alkaloid which comes from the African tree, yohimbe. Sexual desire increases after consumption of other substances such as chocolate and muira puama, which originates from a tree from the Amazon region, with the nickname ‘potency wood’, but none of these substances ensures increased sexual arousal or satisfaction. “Some people feel the effect of the phenylethylamine in chocolate which raises the level of serotonin and endorphins in the brain”, explains Marcone. He adds that the stimulating effect is only really produced in the brain. Saffron has a total effect, both physiological and psychological.

Gula Java Safran
Gula Java Safran
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Boost your sex life with Saffron Saffron and sexual dysfunction Saffron a great help with if you feel depressed