Saffron effective for Alzheimer’s patients
For many years I am using several Amanprana products. My all-time favorites are Kotobuki Matcha, Gula Java Cacao, Gula Java Safran, Coconut Oil, Botanico Mix and Razoli.Marco Zielinski, Geschäftsführer, Rhino's energy GmbH, Germany
Saffron effective in the treatment of Alzheimer's desease,
The world is expecting an "Alzheimer’s tsunami" in the coming 40 years. In the next 40 years the number of people with Alzheimer’s will at least triple (1).
Doctors often prescribe antidepressants to these patients, notably Zoloft (Sertaline) (5), in spite of the fact that the published information relating to them indicates that these medicines aren’t effective in treating Alzheimer’s and often cause adverse side effects (2).
In order to determine whether saffron could offer an alternative treatment, scientists set up a double-blind, randomised and placebo-controlled study. Alzheimer’s patients are given 15 mg saffron or placebo capsules twice a day.
Standard assessment scales were used in order to monitor the cognitive and clinical profiles (3). After 16 weeks it was clear that the saffron group had significantly better cognitive function scores than the placebo group. The author of the study wrote: "In treating Alzheimer’s saffron is both safe and effective in the mild to moderate phase of this disease" (3).
Saffron better than Aricept (Donepezil)In a 22 week long, multi-centre, randomised, double-blind trial on Alzheimer’s sufferers, when compared with the medication Aricept (Donepezil), saffron appeared to be just as effective, but without the negative side effects. A lot of people in the Aricept group experience vomiting as a notable side effect of their medication (4).
1. Available at: http://vitals.nbcnews.com/_news/2013/02/06/ 16872274-alzheimers-numbers-to-triple-by-2050-report-says?lite. Accessed April 19, 2013.
2. Banerjee S, Hellier J, Romeo R, et al. Study of the use of antidepressants for depression in dementia: the HTA-SADD trial - a multicentre, randomised, double-blind, placebo-controlled trial of the clinical effectiveness and cost-effectiveness of sertraline and mirtazapine. Health Technol Assess. 2013 Feb;17(7):1-166.
3. Akhondzadeh S, Sabet MS, Harirchian MH, et al. Saffron in the treatment of patients with mild to moderate Alzheimer’s disease: a 16-week, randomized and placebo-controlled trial. J Clin Pharm Ther. 2010 Oct;35(5):581-8.
4. Akhondzadeh S, Shafiee Sabet M, Harirchian MH, et al. A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer’s disease. Psychopharmacology (Berl). 2010 Jan;207(4):637-43.
5. Modrego PJ. Depression in Alzheimer’s disease. Pathophysiology, diagnosis, and treatment. J Alzheimers Dis. 2010;21(4):1077-87.
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